2122. Assessment and comparison of likely density distributions in the cases of thickness measurement of skin tumours by ultrasound examination and histological analysis

Indre Drulyte1, Tomas Ruzgas2, Renaldas Raisutis3, Skaidra Valiukeviciene4

1, 3Prof. K. Baršauskas Ultrasound Research Institute, Kaunas University of Technology, Kaunas, Lithuania

2Department of Applied Mathematics, Faculty of Mathematics and Natural Sciences,
Kaunas University of Technology, Kaunas, Lithuania

3Department of Electrical Power systems, Faculty of Electrical and Electronics Engineering,
Kaunas University of Technology, Kaunas, Lithuania

4Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Kaunas, Lithuania

1Corresponding author

E-mail: 1drulyte.indre@inbox.lt, 2tomas.ruzgas@ktu.lt, 3renaldas.raisutis@ktu.lt, 4skaidra.valiukeviciene@lsmuni.lt

Received 9 May 2016; received in revised form 14 June 2016; accepted 21 June 2016

DOI https://doi.org/10.21595/jve.2016.17183

Abstract. Ultrasonic diagnostic methods are used to estimate the structural changes and to measure parameters of lesions of the human tissue. Nowadays, the special algorithms of medical data analysis are able to perform diagnosis and monitor the progress of treatment, efficiency of treatment methods, also to estimate the health status and to make prognosis of the diseases evolution. The aim of the presented research is to check the goodness of fit test for thicknesses of the skin tumours measured in two different ways (ultrasound examination and histological analysis) and to compare the compatibility of likely density of histological thicknesses distribution of the skin tumours and density of Normal distribution. As a result, the study has showed that thicknesses of the skin tumours measured by ultrasonic method are strongly similar to histological values, which means that the density of ultrasonic thicknesses distribution and density of Normal distribution are closely interconnected. Therefore, the obtained results show the sufficient level of reliability in the case of application of non-invasive ultrasonic thickness measurement comparing with reference invasive technique based on biopsy and histological thickness evaluation.

Keywords: skin tumour, thickness measurement, goodness of fit test, kernel method, nonparametric density estimator, Monte Carlo method.

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Cite this article

Drulyte Indre, Ruzgas Tomas, Raisutis Renaldas, Valiukeviciene Skaidra Assessment and comparison of likely density distributions in the cases of thickness measurement of skin tumours by ultrasound examination and histological analysis. Journal of Vibroengineering, Vol. 18, Issue 5, 2016, p. 3279‑3291.

 

© JVE International Ltd. Journal of Vibroengineering. Aug 2016, Vol. 18, Issue 5. ISSN 1392-8716